High-quality images are assured only if you are able to remain perfectly still while the images are being recorded. If you are anxious, confused or in severe pain, you may find it difficult to lie still during imaging.
A person who is very obese may not fit into the opening of a conventional MRI machine.
The presence of an implant or other metallic object often makes it difficult to obtain clear images and patient movement can have the same effect.
Breathing may cause artifacts, or image distortions, during MRIs of the chest, abdomen and pelvis. Bowel motion is another source of motion artifacts in abdomen and pelvic MRI studies.
Assessment of the lungs is limited.
MRI generally is not recommended for patients who have been acutely injured. This is because traction devices and life support equipment must be kept away from the area to be imaged. Furthermore, the examination takes longer than other imaging modalities (typically x-ray and CT) and the results may not be immediately available as is often necessary in trauma situations.
Although there is no reason to believe that magnetic resonance imaging harms the fetus, the effects of a strong magnetic field are not well understood. For this reason pregnant women usually are advised not to have an MRI exam unless medically necessary.
MRI may not always distinguish between tumor tissue and edema fluid. It cannot detect calcium present in a tumor. Detection of calcium (in tumors or other issues) is limited with MRI.
MRI typically costs more and may take more time to perform than other imaging modalities.

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